First off, I'm not a game designer/coder, but a music composer - please take this idea with a grain of salt.
I've been looking for games that are "strange" to me. I don't know what is strange to most people, but I have never seen or heard this idea in a game. This could be my own ignorance.
So here goes...
The point of the game would be to escape one's own mind. You, the main character, would have a mental issue of some sort; autism, depression, psychosis, etc.. You would seemingly be placed in a hospital of some sort, a medical ward. You would know, from mental conditioning via media, school, whatever; being in a ward of this type is not a good thing.
The thing is, this ward is inside of your head, so things that happen would not normally happen in reality. Your surroundings would fluctuate, walls aren't always impermeable, other types of things that are perceived normally would react oddly.
When you come across puzzles to solve, which you invariably will, trying to escape from your own mental hospital, there would be several ways to solve the puzzle, and of course, the depending on the solution, you would have different storylines (or not).
Solutions would be "out of the box", not normal.
The final exit would be realized, and when you come out of your own mind, you realize that the world around you is not ordinary, and whatever condition you have is not out of the ordinary. So, you don't "win". You just wake up and realize everything's messed up, just the way it's always been. Nothing has changed.
Now, thinking upon further game-play, maybe you as the main character can have your choice of mental instability. Maybe you are a killer, maybe you are suicidal, maybe you are OCD - who knows. The puzzles would be different for each type of issue, and the game-play would adjust accordingly. You might think picking a different instability would allow you to beat the game, but you never would, because the game can't be beat. Maybe, you can only get "better". Maybe you can get "better" each time you play, and see that the difference around yourself. There is no winning, only getting "better" than you were before.
The game could go on in various ways, and maybe somebody could find other things to do in the game - maybe you walk across a field that is miles across and you find a water pump or something. The game could possibly even allow others to build upon it, and create their own little psychotic worlds.
The reason I am thinking of this idea is because I'm looking for something to compose my music to that actually suits the weirdest of my compositions. I can compose pop and classical and standard sci-fi all day long, but it would be neat to use my music that is "nuts", abnormal, to this:
Yeah, I'm showboating a little, but hey, it's a neat idea, and I'd actually play this game. No losing, only learning. Plus it could be a game that you could play a lot. I'm influenced by the game "Out of This World", that I played on the Super Nintendo.
Seriously, what do you think? Is this a horrible idea? Would there be anybody interested in working with me on such a project? I'd like to learn more about game-making myself, so who knows what could come of this?